
Maternal and Child Health Library
MCH Alert: Focus on Infant Mortality is developed by the Maternal
and Child Health Library in collaboration with the National Sudden
and Unexpected Infant/Child and Pregnancy Loss Resource Center at
Georgetown University. This
and past issues are available online
at http://www.mchlibrary.info/alert/archives.html and http://www.sidscenter.org/alert/archives.html.
April 30, 2010
Readers: This issue includes summaries that reference stillbirth and
perinatal death. The terms "stillbirth," "perinatal death," and
"perinatal loss" are often used interchangeably. In writing these
summaries, we have tried to use terms as accurately as possible while
also being true to the language used in the original articles.
Multimedia Featured Resource: Community Journeys to Reduce Infant
Mortality by Addressing Racism: Translating Learning into Action
describes how three national organizations and six communities across
the country worked together to translate research and knowledge into
action around racism. The Webinar was co-produced by CityMatCH and the
National Association of County and City Health Officials as part of the
Emerging Issues in MCH (E-MCH) series, presenting current research,
policy, and practice strategies on critical issues in public health.
The Webinar detailed the Infant Mortality and Racism Action Learning
Collaborative, an activity of the Partnership to Eliminate Disparities
in Infant Mortality. The partnership, which aims to decrease racial
disparities in infant mortality in urban areas, comprises CityMatCH,
the Association of Maternal and Child Health Programs, and the National
Healthy Start Association and is supported by the W.K. Kellogg
Foundation. Webinar topics included (1) key differences between health
disparities and health equity, (2) processes by which teams can
effectively approach and address racism, (3) the role of local and
state health departments and other community organizations in reducing
infant mortality by addressing racism, and (4) resources for local
health departments. The Webinar archive (presenter information,
recording, and materials) is available at https://cc.readytalk.com/cc/schedule/display.do?udc=n39dse7u2d95
1. Toolkit Provides Guidance on Creating Practice
Environments Where Clients of All Literacy Levels Can Thrive
2. Survey Examines Obstetricians' Advice About Optimal
Timing of Next Pregnancy Following Perinatal Death
3. Article Assesses Influence of Advice and Mothers'
Beliefs on Infant Sleep Position
4. Authors Investigate the Association Between Prior
Pre-Eclampsia and Subsequent Stillbirth in Black Women and White Women
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1. TOOLKIT PROVIDES GUIDANCE ON CREATING PRACTICE ENVIRONMENTS WHERE
CLIENTS OF ALL LITERACY LEVELS CAN THRIVE
Health Literacy Universal Precautions Toolkit provides step-by-step
guidance and tools for physicians and other primary care health
professionals to use in assessing a practice and making changes to
promote better understanding for clients of all literacy levels. The
Agency for Healthcare Research and Quality commissioned the University
of North Carolina at Chapel Hill to produce the toolkit. Contents
include tools for practice change, video, documents, Internet
resources, testimonials from a practice, tips, and key points. Topics
include an overview of health literacy universal precautions, steps to
implement the toolkit, and instructions on identifying and addressing
areas that need improvement (spoken and written communication,
self-management and empowerment, and supportive systems). The appendix
contains resources such as forms, PowerPoint presentations, worksheets,
and posters that support the implementation of the tools. The toolkit
and additional resources related to the toolkit are available at http://www.ahrq.gov/qual/literacy
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2. SURVEY EXAMINES OBSTETRICIANS' ADVICE ABOUT OPTIMAL TIMING OF NEXT
PREGNANCY FOLLOWING PERINATAL DEATH
"This study highlights physician recommendations for brief IPI
(interpregnancy interval) after a stillbirth," state the authors of an
article published in the April 2010 issue of the American Journal of
Obstetrics and Gynecology. Multiple studies have demonstrated that a
waiting period of 6 to 18 months between pregnancies reduces the risk
of adverse outcomes. Multiple studies have demonstrated that a waiting
period of 6-18 months between pregnancies reduces the risk of adverse
outcomes. Optimal timing of subsequent pregnancy after stillbirth or
early infant death (perinatal death) is complicated by the varied grief
and emotional responses of bereaved parents to the loss and by the
psychological challenges of the next pregnancy. The article describes
findings from a national survey to solicit U.S. obstetricians' opinions
about their recommendations for optimal timing of a subsequent
pregnancy after perinatal death, including their beliefs about when
parents are medically and emotionally prepared for another pregnancy.
The researchers sent a 51-question survey to 1,500 obstetricians
selected through random sampling from the American Medical Association
(AMA) Physician Masterfile and confirmed to hold an active U.S. medical
license. The sample included AMA members and nonmembers, as well as
graduates of foreign medical schools who live in the United States. The
survey assessed care at the time of perinatal death, opinions about
subsequent conception and pregnancy after perinatal death, personal
impact of caring for patients with a loss, and demographic variables.
The researchers also evaluated associations between outcomes of
interest and years of experience, race, sex, professional position,
personal or family experience with a perinatal death, being a parent,
and current practice of obstetric deliveries (not reported here).
The authors found that
- The analyses included 804 completed surveys (response rate = 54
percent).
- Twenty-seven percent of physicians responded that, following a
perinatal death, parents could try to conceive "as soon as they feel
ready"; 10 percent recommended waiting for one or more normal menses;
33 percent recommended two to five normal menses; and 31 percent
recommended waiting 6 or more months.
- Forty-five percent of physicians responded that parents would not
be emotionally ready to conceive until 6 or more months after a
perinatal death; 40 percent responded "as soon as they feel ready"; 1
percent recommended one or more normal menses; and 13 percent
recommended two to five normal menses.
- Thirty-two percent of physicians responded that parents would not
be medically ready to conceive until 6 or more months after a perinatal
death; 9 percent responded that parents would be medically ready "as
soon as they are ready"; 19 percent recommended one or more normal
menses; and 40 percent recommended two to five normal menses.
- Forty-two percent of physicians responded that parents "often" or
"usually" wait to conceive as long as suggested; 13 percent responded
that parents "rarely" or "not so often," waited; and 44 percent
responded, "it varies."
"In this survey, less than a third of physicians recommended that
parents bereaved by stillbirth wait [6 or more] months prior to trying
for conception. This is an important finding and warrants additional
exploration of the complicated issues presented by a perinatal death,"
state the authors.
Gold KJ, Leon I, Chames MC. 2010. National survey of obstetrician
attitudes about timing the subsequent pregnancy after perinatal death.
American Journal of Obstetrics and Gynecology 202(4):357.e1-357.e6.
Abstract available at http://www.ajog.org/article/S0002-9378%2809%2902213-3/abstract
Readers: More information is available from the following MCH Library
resources:
- Infant Mortality and Pregnancy Loss: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_infmort.html
- Preconception and Pregnancy: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_pregnancy.html
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3. ARTICLE ASSESSES INFLUENCE OF ADVICE AND MOTHERS' BELIEFS ON INFANT
SLEEP POSITION
"In this study of predominantly African American mothers, we have shown
that advice supporting exclusively supine position from many different
sources increases the chance that a mother will place her infant supine
for sleep and that there is a dose-response effect of advice for
exclusively supine sleep," write the authors of an article published in
the April 2010 issue of Archives of Pediatrics and Adolescent Medicine.
Research has found that African-American infants are much less likely
than white infants to be placed supine to sleep. Since the American
Academy of Pediatrics issued its first recommendation in 1992 that all
infants be place supine to sleep, the incidence of SIDS among African
Americans has not decreased to the lower rates observed among other
groups who more commonly place infants supine. Earlier studies of the
general population of the United State has shown that advice mothers
receive about infant sleep position and their beliefs are important
predictors of sleep position. The goal of the study described in this
article was to determine the relationship between advice mothers
receive about infant sleep position and actual infant sleep position
and to understand the effect of potential modifiers of that
relationship, such as beliefs about infant comfort and choking, among a
group of low-income, mostly African-American mothers who are at high
risk of placing their infants nonsupine to sleep. A total of 2,229
mothers were included in the analysis; of these, 1,689 (74 percent)
were African American.
In 2006, 2007, and 2008, the authors conducted face-to-face interviews
with mothers of infants younger than age 8 months at WIC programs in
six cities: Birmingham, AL; New Haven, CT; Detroit, MI; Clarksdale, MI;
Jackson, MI; and Dallas, TX (all of which served at least 50 percent
African-American clients). The outcome of interest was usually supine
infant sleep position for all sleep periods (daytime and nighttime)
during the past 2 weeks. Predictor variables were the advice mothers
reported receiving about infant sleep position and maternal perceptions
about infant comfort and choking.
The authors found that
- A total of 1,408 (61 percent) mothers reported usually placing
their infants supine to sleep; 489 (21 percent) lateral; 390 (17
percent) prone; and 12 (0.5 percent) another position.
- The percentage of mothers who placed their infants supine
increased with higher advice scores (number of sources of advice for
exclusively supine sleep minus number of sources of advice for not
exclusively supine sleep).
- Mothers who believed their infants were most comfortable supine
were more likely to usually place their infants supine; those who
believed that infants were most likely to choke supine were
significantly less likely to usually place their infants supine.
- Advice for exclusively supine sleep from most sources was
associated with higher odds of usual supine sleep position after
adjustment for covariates.
- Throughout the analyses, mothers' beliefs about infant comfort
and choking remained significant. Race-ethnicity, a significant
predictor of usually supine infant sleep in the initial analysis,
became nonsignificant once mothers' beliefs were included and remained
nonsignificant in all subsequent models.
The authors conclude that "increasing advice for exclusively supine
sleep, especially through the media, and addressing mothers' concerns
about infant comfort and choking are critical to getting more infants
on their backs to sleep."
von Kohorn I, Corwin MJ, Rybin DV, et al. 2010. Influence of prior
advice and beliefs of mothers on infant sleep position. Archives of
Pediatrics and Adolescent Medicine 164(4):363-369. Abstract available
at http://archpedi.ama-assn.org/cgi/content/short/164/4/363
Readers: More information is available from the National Sudden
Unexpected Infant-Child Death and Pregnancy Loss Resource Center's Web
site as follows:
- Safe Sleep Environment at
http://www.sidscenter.org/SafeSleep/index.html
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4. AUTHORS INVESTIGATE THE ASSOCIATION BETWEEN PRIOR PRE-ECLAMPSIA AND
SUBSEQUENT STILLBIRTH IN BLACK WOMEN AND WHITE WOMEN
Our analysis showed that "prior pre-eclampsia in association with early
gestational age amplified the risk of stillbirth in the second
pregnancy. However, we did not find any increased risk for stillbirth
in women with prior late-onset pre-eclampsia," state the authors of an
article published in the April 2010 issue of the European Journal of
Obstetrics and Gynecology and Reproductive Biology. Although the
association between onset of pre-eclampsia and stillbirth in the
concurrent pregnancy is well established, there is conflicting evidence
for the notion that pre-eclampsia is a marker for stillbirth in future
pregnancies. The article presents findings from a retrospective cohort
study to examine the association between prior pre-eclampsia and future
risk for stillbirth in the second pregnancy in a heterogeneous
population comprising white and black mothers.
Data were drawn from the Missouri maternally linked cohort data files
covering the period 1989 to 2005. (The data source contained
information on both live birth and fetal death for each sibling and
provided a platform for a longitudinal study of birth outcomes for each
pregnancy.) The analysis included women with first and second singleton
pregnancies with the gestational age range of 20-44 weeks. The first
pregnancy was limited to live births only. Pre-eclampsia was defined as
a diastolic blood pressure of at least 90 mm Hg accompanied by
proteinuria, and eclampsia was considered a worsening progression of
pre-eclampsia. The study population was categorized into an exposure
group (women who experienced pre-eclampsia or eclampsia in their first
pregnancy) and a comparison group (women who had no pre-eclampsia or
eclampsia in their first pregnancy). Women with prior pre-eclampsia
were further classified according to the gestational age of occurrence
of the disease into two groups: early-onset pre-eclampsia (before 34
weeks of gestation) and late-onset pre-eclampsia (34 weeks and beyond).
The women were followed up to their second pregnancies and pregnancy
outcome was evaluated. The occurrence of stillbirth in the second
pregnancy was the main outcome of interest.
The authors found that
- Overall, women who experienced pre-eclampsia in their first
pregnancy had a 43 percent increased risk of stillbirth in their second
pregnancy.
- Whereas women with a history of late-onset pre-eclampsia had no
elevated risk of stillbirth when compared with women who did not
experience pre-eclampsia in their first pregnancy, women whose first
pregnancy resulted in early-onset- pre-eclampsia had a more than
fourfold increased risk of stillbirth in their second pregnancy.
- Black women whose prior pregnancies resulted in early-onset
pre-eclampsia had a more than eightfold increased risk of stillbirth
compared to their counterparts whose prior pregnancies were free of the
disease. By contrast, the risk of stillbirth in black women with
late-onset pre-eclampsia in their first pregnancy was not different
from that of black women without pre-eclampsia in their first pregnancy.
"Unique to our study is the observation of an important racial
difference in the association between prior pre-eclampsia and
stillbirth occurrence in subsequent pregnancy," the authors conclude,
adding that health professionals may find the results useful during
inter-pregnancy counseling of women with previous pre-eclampsia.
Mbah AK, Alio AP, Marty PJ, et al. 2010. Pre-eclampsia in the first
pregnancy and subsequent risk of stillbirth in black and white
gravidas. European Journal of Obstetrics and Gynecology and
Reproductive Biology 149(2):165-169. Abstract available at http://www.ejog.org/article/S0301-2115%2810%2900005-9/abstract
Readers: More information is available from the National Sudden and
Unexpected Infant/Child Death and Pregnancy Loss Resource Center at
Georgetown University as follows:
- Stillbirth at
http://sidscenter.org/AZtopics/S.html#s15
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MCH Alert © 1998-2010 by National Center for Education in Maternal
and
Child Health and Georgetown University. MCH Alert: Focus on Infant
Mortality is produced by
Maternal and Child Health Library at the National Center for Education
in Maternal and Child Health at Georgetown University under its
cooperative agreements
(U02MC00001 and U48MC08717) with the Maternal and Child Health Bureau,
Health
Resources and Services Administration, U.S. Department of Health and
Human Services. The Maternal and Child Health Bureau reserves a
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Permission is given to forward MCH Alert, in its entirety, to others.
For
all other uses, requests for permission to duplicate and use all or
part of the information contained in this publication should be sent to mchalert@ncemch.org.
The editors welcome your submissions, suggestions, and questions.
Please contact us at the address below.
EDITOR/ADMINISTRATOR: Jolene Bertness, M.Ed.
CO-EDITOR: Tracy Lopez, M.S.L.S.
COPYEDITOR/WRITER: Ruth Barzel, M.A.
WRITER: Beth DeFrancis, M.L.S.
MCH Alert
Maternal and Child Health Library
National Center for Education in Maternal and Child Health
Georgetown University
Box 571272
Washington, DC 20057-1272
Phone: (202) 784-9770
Fax: (202) 784-9777
E-mail: mchalert@ncemch.org
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