MCH Alert: Focus on Infant Mortality


Maternal and Child Health Library

MCH Alert: Focus on Infant Mortality is developed by the Maternal and Child Health Library in collaboration with the National Sudden and Unexpected Infant/Child and Pregnancy Loss Resource Center at Georgetown University. This and past issues are available online at http://www.mchlibrary.info/alert/archives.html and http://www.sidscenter.org/alert/archives.html.


April 30, 2010

Readers: This issue includes summaries that reference stillbirth and perinatal death. The terms "stillbirth," "perinatal death," and "perinatal loss" are often used interchangeably. In writing these summaries, we have tried to use terms as accurately as possible while also being true to the language used in the original articles.

Multimedia Featured Resource: Community Journeys to Reduce Infant Mortality by Addressing Racism: Translating Learning into Action describes how three national organizations and six communities across the country worked together to translate research and knowledge into action around racism. The Webinar was co-produced by CityMatCH and the National Association of County and City Health Officials as part of the Emerging Issues in MCH (E-MCH) series, presenting current research, policy, and practice strategies on critical issues in public health. The Webinar detailed the Infant Mortality and Racism Action Learning Collaborative, an activity of the Partnership to Eliminate Disparities in Infant Mortality. The partnership, which aims to decrease racial disparities in infant mortality in urban areas, comprises CityMatCH, the Association of Maternal and Child Health Programs, and the National Healthy Start Association and is supported by the W.K. Kellogg Foundation. Webinar topics included (1) key differences between health disparities and health equity, (2) processes by which teams can effectively approach and address racism, (3) the role of local and state health departments and other community organizations in reducing infant mortality by addressing racism, and (4) resources for local health departments. The Webinar archive (presenter information, recording, and materials) is available at https://cc.readytalk.com/cc/schedule/display.do?udc=n39dse7u2d95

1. Toolkit Provides Guidance on Creating Practice Environments Where Clients of All Literacy Levels Can Thrive
2. Survey Examines Obstetricians' Advice About Optimal Timing of Next Pregnancy Following Perinatal Death
3. Article Assesses Influence of Advice and Mothers' Beliefs on Infant Sleep Position
4. Authors Investigate the Association Between Prior Pre-Eclampsia and Subsequent Stillbirth in Black Women and White Women

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1. TOOLKIT PROVIDES GUIDANCE ON CREATING PRACTICE ENVIRONMENTS WHERE CLIENTS OF ALL LITERACY LEVELS CAN THRIVE

Health Literacy Universal Precautions Toolkit provides step-by-step guidance and tools for physicians and other primary care health professionals to use in assessing a practice and making changes to promote better understanding for clients of all literacy levels. The Agency for Healthcare Research and Quality commissioned the University of North Carolina at Chapel Hill to produce the toolkit. Contents include tools for practice change, video, documents, Internet resources, testimonials from a practice, tips, and key points. Topics include an overview of health literacy universal precautions, steps to implement the toolkit, and instructions on identifying and addressing areas that need improvement (spoken and written communication, self-management and empowerment, and supportive systems). The appendix contains resources such as forms, PowerPoint presentations, worksheets, and posters that support the implementation of the tools. The toolkit and additional resources related to the toolkit are available at http://www.ahrq.gov/qual/literacy

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2. SURVEY EXAMINES OBSTETRICIANS' ADVICE ABOUT OPTIMAL TIMING OF NEXT PREGNANCY FOLLOWING PERINATAL DEATH

"This study highlights physician recommendations for brief IPI (interpregnancy interval) after a stillbirth," state the authors of an article published in the April 2010 issue of the American Journal of Obstetrics and Gynecology. Multiple studies have demonstrated that a waiting period of 6 to 18 months between pregnancies reduces the risk of adverse outcomes. Multiple studies have demonstrated that a waiting period of 6-18 months between pregnancies reduces the risk of adverse outcomes. Optimal timing of subsequent pregnancy after stillbirth or early infant death (perinatal death) is complicated by the varied grief and emotional responses of bereaved parents to the loss and by the psychological challenges of the next pregnancy. The article describes findings from a national survey to solicit U.S. obstetricians' opinions about their recommendations for optimal timing of a subsequent pregnancy after perinatal death, including their beliefs about when parents are medically and emotionally prepared for another pregnancy.

The researchers sent a 51-question survey to 1,500 obstetricians selected through random sampling from the American Medical Association (AMA) Physician Masterfile and confirmed to hold an active U.S. medical license. The sample included AMA members and nonmembers, as well as graduates of foreign medical schools who live in the United States. The survey assessed care at the time of perinatal death, opinions about subsequent conception and pregnancy after perinatal death, personal impact of caring for patients with a loss, and demographic variables. The researchers also evaluated associations between outcomes of interest and years of experience, race, sex, professional position, personal or family experience with a perinatal death, being a parent, and current practice of obstetric deliveries (not reported here).

The authors found that
"In this survey, less than a third of physicians recommended that parents bereaved by stillbirth wait [6 or more] months prior to trying for conception. This is an important finding and warrants additional exploration of the complicated issues presented by a perinatal death," state the authors.

Gold KJ, Leon I, Chames MC. 2010. National survey of obstetrician attitudes about timing the subsequent pregnancy after perinatal death. American Journal of Obstetrics and Gynecology 202(4):357.e1-357.e6. Abstract available at http://www.ajog.org/article/S0002-9378%2809%2902213-3/abstract

Readers: More information is available from the following MCH Library resources:

- Infant Mortality and Pregnancy Loss: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_infmort.html

- Preconception and Pregnancy: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_pregnancy.html

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3. ARTICLE ASSESSES INFLUENCE OF ADVICE AND MOTHERS' BELIEFS ON INFANT SLEEP POSITION

"In this study of predominantly African American mothers, we have shown that advice supporting exclusively supine position from many different sources increases the chance that a mother will place her infant supine for sleep and that there is a dose-response effect of advice for exclusively supine sleep," write the authors of an article published in the April 2010 issue of Archives of Pediatrics and Adolescent Medicine. Research has found that African-American infants are much less likely than white infants to be placed supine to sleep. Since the American Academy of Pediatrics issued its first recommendation in 1992 that all infants be place supine to sleep, the incidence of SIDS among African Americans has not decreased to the lower rates observed among other groups who more commonly place infants supine. Earlier studies of the general population of the United State has shown that advice mothers receive about infant sleep position and their beliefs are important predictors of sleep position. The goal of the study described in this article was to determine the relationship between advice mothers receive about infant sleep position and actual infant sleep position and to understand the effect of potential modifiers of that relationship, such as beliefs about infant comfort and choking, among a group of low-income, mostly African-American mothers who are at high risk of placing their infants nonsupine to sleep. A total of 2,229 mothers were included in the analysis; of these, 1,689 (74 percent) were African American.

In 2006, 2007, and 2008, the authors conducted face-to-face interviews with mothers of infants younger than age 8 months at WIC programs in six cities: Birmingham, AL; New Haven, CT; Detroit, MI; Clarksdale, MI; Jackson, MI; and Dallas, TX (all of which served at least 50 percent African-American clients). The outcome of interest was usually supine infant sleep position for all sleep periods (daytime and nighttime) during the past 2 weeks. Predictor variables were the advice mothers reported receiving about infant sleep position and maternal perceptions about infant comfort and choking.

The authors found that
The authors conclude that "increasing advice for exclusively supine sleep, especially through the media, and addressing mothers' concerns about infant comfort and choking are critical to getting more infants on their backs to sleep."

von Kohorn I, Corwin MJ, Rybin DV, et al. 2010. Influence of prior advice and beliefs of mothers on infant sleep position. Archives of Pediatrics and Adolescent Medicine 164(4):363-369. Abstract available at http://archpedi.ama-assn.org/cgi/content/short/164/4/363

Readers: More information is available from the National Sudden Unexpected Infant-Child Death and Pregnancy Loss Resource Center's Web site as follows:

- Safe Sleep Environment at
http://www.sidscenter.org/SafeSleep/index.html

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4. AUTHORS INVESTIGATE THE ASSOCIATION BETWEEN PRIOR PRE-ECLAMPSIA AND SUBSEQUENT STILLBIRTH IN BLACK WOMEN AND WHITE WOMEN

Our analysis showed that "prior pre-eclampsia in association with early gestational age amplified the risk of stillbirth in the second pregnancy. However, we did not find any increased risk for stillbirth in women with prior late-onset pre-eclampsia," state the authors of an article published in the April 2010 issue of the European Journal of Obstetrics and Gynecology and Reproductive Biology. Although the association between onset of pre-eclampsia and stillbirth in the concurrent pregnancy is well established, there is conflicting evidence for the notion that pre-eclampsia is a marker for stillbirth in future pregnancies. The article presents findings from a retrospective cohort study to examine the association between prior pre-eclampsia and future risk for stillbirth in the second pregnancy in a heterogeneous population comprising white and black mothers.

Data were drawn from the Missouri maternally linked cohort data files covering the period 1989 to 2005. (The data source contained information on both live birth and fetal death for each sibling and provided a platform for a longitudinal study of birth outcomes for each pregnancy.) The analysis included women with first and second singleton pregnancies with the gestational age range of 20-44 weeks. The first pregnancy was limited to live births only. Pre-eclampsia was defined as a diastolic blood pressure of at least 90 mm Hg accompanied by proteinuria, and eclampsia was considered a worsening progression of pre-eclampsia. The study population was categorized into an exposure group (women who experienced pre-eclampsia or eclampsia in their first pregnancy) and a comparison group (women who had no pre-eclampsia or eclampsia in their first pregnancy). Women with prior pre-eclampsia were further classified according to the gestational age of occurrence of the disease into two groups: early-onset pre-eclampsia (before 34 weeks of gestation) and late-onset pre-eclampsia (34 weeks and beyond). The women were followed up to their second pregnancies and pregnancy outcome was evaluated. The occurrence of stillbirth in the second pregnancy was the main outcome of interest.

The authors found that
"Unique to our study is the observation of an important racial difference in the association between prior pre-eclampsia and stillbirth occurrence in subsequent pregnancy," the authors conclude, adding that health professionals may find the results useful during inter-pregnancy counseling of women with previous pre-eclampsia.

Mbah AK, Alio AP, Marty PJ, et al. 2010. Pre-eclampsia in the first pregnancy and subsequent risk of stillbirth in black and white gravidas. European Journal of Obstetrics and Gynecology and Reproductive Biology 149(2):165-169. Abstract available at http://www.ejog.org/article/S0301-2115%2810%2900005-9/abstract

Readers: More information is available from the National Sudden and Unexpected Infant/Child Death and Pregnancy Loss Resource Center at Georgetown University as follows:

- Stillbirth at
http://sidscenter.org/AZtopics/S.html#s15

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MCH Alert © 1998-2010 by National Center for Education in Maternal and Child Health and Georgetown University. MCH Alert: Focus on Infant Mortality is produced by Maternal and Child Health Library at the National Center for Education in Maternal and Child Health at Georgetown University under its cooperative agreements (U02MC00001 and U48MC08717) with the Maternal and Child Health Bureau, Health Resources and Services Administration, U.S. Department of Health and Human Services. The Maternal and Child Health Bureau reserves a royalty-free, nonexclusive, and irrevocable right to use the work for federal purposes and to authorize others to use the work for federal purposes.
 
Permission is given to forward MCH Alert, in its entirety, to others. For all other uses, requests for permission to duplicate and use all or part of the information contained in this publication should be sent to mchalert@ncemch.org.

The editors welcome your submissions, suggestions, and questions. Please contact us at the address below.

EDITOR/ADMINISTRATOR: Jolene Bertness, M.Ed.
CO-EDITOR: Tracy Lopez, M.S.L.S.
COPYEDITOR/WRITER: Ruth Barzel, M.A.
WRITER: Beth DeFrancis, M.L.S.

MCH Alert
Maternal and Child Health Library
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