
Maternal and Child Health Library
MCH Alert: Focus on Infant Mortality is developed by the Maternal
and Child Health Library in collaboration with the National Sudden
and Unexpected Infant/Child and Pregnancy Loss Resource Center at
Georgetown University. This
and past issues are available online
at http://www.mchlibrary.info/alert/archives.html
and http://www.sidscenter.org/alert/archives.html.
August 28, 2009
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Special Notices:
In recognition of National Infant Mortality Awareness Month (September
2009), the National Healthy Start Association has produced a toolkit to
help Healthy Start projects promote the effectiveness of programs and
efforts to reduce infant deaths, low birthweight, preterm births, and
disparities in perinatal outcomes. The toolkit is available at
http://www.healthystartassoc.org/Toolkit.pdf.
Additional information
and resources are available from the Office of Minority Health's
campaign, A Healthy Baby Begins with You, at http://www.omhrc.gov/templates/browse.aspx?lvl=2&lvlid=117
FINAL CALL: If you have not yet completed the 2009 MCH Alert Reader
Feedback Form, please take a few moments to answer the questions and
submit your comments at
https://www.surveymonkey.com/s.aspx?sm=16ZJG5kXZgVQC_2bHc_2bxFH6A_3d_3d
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1. National Center Compiles Resources on the Topics of
Bedsharing and Co-Sleeping, Swaddling, and Shaken Baby Syndrome
2. Report Explores Network of U.S. Global Health
Activities
3. Review Highlights Advances in Understanding Sudden
Infant Death Syndrome
4. Authors Examine the Role of Pediatric Resuscitation in
the Community Hospital Setting on Improving Child Health Outcomes
5. Study Evaluates Interventions' Effectiveness At
Resolving Couples' Depression and Grief After Miscarriage
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1. NATIONAL CENTER COMPILES RESOURCES ON THE TOPICS OF BEDSHARING
AND CO-SLEEPING, SWADDLING, AND SHAKEN BABY SYNDROME
The National Sudden and Unexpected Infant-Child Death and Pregnancy
Loss Resource Center's Web site includes an updated bibliography on bed
sharing, co-sleeping, and sudden infant death syndrome (SIDS) and one
on swaddling and SIDS. Each bibliography presents definitions and lists
recent citations and abstracts from peer-reviewed journals. The
bibliographies also include a customized tool that can be used to
search PubMed for additional articles. The bibliographies are available
as follows:
The Center's Web site also features a new A-Z Topics section: Shaken
Baby Syndrome (Abusive Head Trauma). Contents include selected
resources from the National Center on Shaken Baby Syndrome, the
Colorado Prevention Campaign, MedlinePlus, KidsHealth from Nemours, and
the National Institute of Neurological Disorders. The section is
available at http://www.sidscenter.org/AZtopics/S.html#s6
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2. REPORT EXPLORES NETWORK OF U.S. GLOBAL HEALTH ACTIVITIES
U.S. Global Health Policy: Mapping the United States Government
Engagement in Global Public Health presents a portfolio analysis of
U.S. government (USG) global health programs to help decision-makers
understand the scope and organization of programs, policies,
authorities, funding, and coordinating mechanisms that comprise U.S.
support for public health abroad. The report is based on research
conducted by the Stimson Center and was produced by the Kaiser Family
Foundation with support from the Bill and Melinda Gates Foundation. The
authors define the scope of USG global health activities as well as
several broad categories for such activities, including disease
detection and response; health-systems strengthening; nutrition; safe
water, sanitation, and mitigating environmental hazards; population and
maternal and child health; and research. The report describes USG
institutions, agencies, and organizations that play some role in U.S.
global health engagement, as well as the existing formal USG mechanisms
to coordinate interagency global health efforts. An overview of all USG
budgets for global health programs by agency and account, including
emergency supplemental appropriations, is included. Conclusions are
also provided. The report is available at http://www.stimson.org/globalhealth/pdf/US_Engagement_in_Global_Public_Health.pdf
Readers: This report provided background research used to inform the
development of the Kaiser Family Foundation's report, The U.S.
Government's Global Health Policy Architecture: Structure, Programs,
and Funding (April 2009) available at http://www.kff.org/globalhealth/7881.cfm
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3. REVIEW HIGHLIGHTS ADVANCES IN UNDERSTANDING SUDDEN INFANT DEATH
SYNDROME
"Current evidence suggests that SIDS [sudden infant death syndrome]
involves a convergence of stressors that probably results in asphyxia
of a vulnerable infant who has defective cardiorespiratory or arousal
defense systems during a critical developmental period when immature
defense mechanisms are not fully integrated," state the authors of an
article published in the August 20, 2009, issue of The New England
Journal of Medicine. SIDS has been substantially demystified in recent
years by major advances in our understanding of its relationship to
sleep and homeostasis, environmental and genetic risk factors, and
biochemical and molecular abnormalities. However, SIDS still remains
the leading cause of postneonatal infant death in the United States and
is the third leading cause of infant mortality overall. This review
highlights the major advances in our understanding of SIDS.
Topics include the definition and incidence of SIDS, causes of sudden
and unexpected infant death, newer models for SIDS, risk factors for
SIDS, putative terminal pathways for SIDS, and asphyxia-related sudden
deaths. Recommendations for risk reduction and counseling are also
presented.
The authors found that
- Risk-reduction recommendations include putting infants to bed in
the supine position on a firm mattress, preferably with a pacifier
(mechanism unknown) and in a shared room (but in a separate bed).
- Important counseling strategies for families with infants who
have died of SIDS have been devised. Of major concern in such families
is the risk of SIDS in subsequent siblings. Although in such cases
there is an increase in risk, it is minimal.
"Our current understanding of the pathogenesis of SIDS reflects the
simultaneous juxtaposition of multiple events that, when taken
individually, are far less powerful than the result of their chance
combination," state the authors. They conclude that "SIDS remains a
major problem that mandates continued interdisciplinary efforts for its
ultimate resolution."
Kinney HC, Thach BT. 2009. The sudden infant death syndrome. The New
England Journal of Medicine 361(8):795-805. Extract available at http://content.nejm.org/cgi/content/short/361/8/795??eaf
Readers: More information is available from the following MCH Library
resource:
- Infant Mortality and Pregnancy Loss: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_infmort.html
Information is also available from the National Sudden and Unexpected
Infant/Child Death and Pregnancy Loss Resource Center at Georgetown
University as follows:
- Sudden Infant Death Syndrome (SIDS) at
http://www.sidscenter.org/AZtopics/S.html#s17
- Sudden Unexplained Infant Death at
http://www.sidscenter.org/AZtopics/S.html#s19
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4. AUTHORS EXAMINE THE ROLE OF PEDIATRIC RESUSCITATION IN THE COMMUNITY
HOSPITAL SETTING ON IMPROVING CHILD HEALTH OUTCOMES
"These observations support the relevance of [pediatric advanced life
support (PALS) and advanced pediatric life support (APLS)]
recommendations to improve child health outcomes in infants and
children with shock in the community setting, regardless of trauma
status," state the authors of an article published in the August 2009
issue of Pediatrics. Emergency Medical Services for Children was
established in 1991 to improve the pediatric emergency care
infrastructure throughout the United States. While most infants and
children access their initial care at community hospitals, those who
require pediatric-specialized care are subsequently transferred to
regional pediatric centers. PALS and APLS curricula concentrate on
improving health professionals' ability to recognize early warning
signs and symptoms and on providing time-sensitive resuscitative
therapies to prevent cardiac arrest and ensuing mortality and
neurologic morbidity. The article presents findings from a study to
evaluate consecutive infants and children with trauma and nontrauma
diagnoses, referred from community hospitals for transport to five
different pediatric centers.
Data were extracted from a multicenter database that had been collected
prospectively over a 4-year period from five regional pediatric
centers' specialty care transport teams. Data were categorized in two
time intervals. Index 1 was defined as the 12 hours before and
including the time of transfer request until the "time the transport
team arrived at the community hospital." Index 2 was defined as the
"time from transport team arrival at the community hospital" to the
"time of the transport team's return to the pediatric center." The
initial analysis estimated the treatment effect in infants or children
receiving resuscitation practice consistent with PALS-APLS guidelines
at index 1. A subsequent model evaluated whether receiving
PALS-APLS-directed therapies at the community hospital remained
associated with improved outcome after controlling for center.
The authors found that
- Thirty-seven percent of the infants and children (N=1,803)
fulfilled the study definition of shock at index 1, index 2, or both.
- The mortality rate was highest in infants and children with
shock, regardless of trauma status: 28.3 percent in trauma infants and
children with shock compared with 1.2 percent in those without shock
and 10.5 percent in nontrauma infants and children with shock compared
with 2.8 percent in those without shock.
- Early reversal of shock in the community hospital emergency
department was associated with reduced mortality (5.06 percent vs.
16.37 percent) and functional morbidity rates (1.56 percent vs. 4.11
percent).
- Early use of therapies consistent with PALS-APLS-recommended
guidelines in the community hospital emergency department was
associated with a decrease in the shock index (heart rate and systolic
blood pressure).
- Community hospital-emergency department delivery of therapy
consistent with PALS-APLS recommendations was associated with a
reduction in mortality (8.69 percent vs. 15.01 percent) and functional
morbidity (1.24 percent vs. 4.23 percent) rates.
- Early implementation of PALS-APLS therapy remained associated
with reduced mortality and functional morbidity rates after controlling
for center, trauma status, and severity of illness.
The authors conclude that "these data support an Emergency Medical
Services for Children organizational approach, which promotes (1) early
recognition of shock with early implementation of resuscitation in the
community hospital and (2) subsequent access to shock-trauma systems
that care for children in shock regardless of trauma status."
Carcillo JA, Kuch BA, Han YY, et al. 2009. Mortality and functional
morbidity after use of PALS/APLS by community physicians. Pediatrics
124(2):500-508. Abstract available at http://pediatrics.aappublications.org/cgi/content/abstract/124/2/500
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5. STUDY EVALUATES INTERVENTIONS' EFFECTIVENESS AT RESOLVING COUPLES'
DEPRESSION AND GRIEF AFTER MISCARRIAGE
"Our study and the research of others suggest that [after miscarriage]
couples desire validation of the meaningfulness of their experience,
guidance on strategies to deal with their loss, and information on ways
to care for each other," write the authors of an article published in
the August 2009 issue of the Journal of Women’s Health. Approximately
15 percent of pregnancies end in miscarriage. In the days surrounding
miscarriage, the majority of women experience grief, depression, or
both. Women's sadness may last up to 1 year after loss. Six months
after miscarrying, women who are most depressed are least likely to
have partners willing to talk about the miscarriage. Men 's greatest
concern after miscarriage tends to be the well-being of their partner,
yet, fearing they might say the wrong thing, many resort to saying
nothing. The authors of this article sought to test the following two
hypotheses: (1) during the first year after miscarriage, women and men
randomized to nurse caring (NC), self-caring (SC), or combined caring
(CC) will exhibit faster rates of recovery from depression, pure grief,
and grief-related emotions than those randomized to no treatment and
(2) during the first year after miscarriage, there will be no
differences in rates of recovery from depression, pure grief, and
grief-related emotions for women and men receiving MC, SC, or CC.
The authors randomly allocated 341 couples to NC (three counseling
sessions), SC (three video and workbook modules), CC (one counseling
session plus three video and workbook modules), or control (no
treatment). Interventions were offered 1, 5, and 11 weeks after
enrollment in the study. Data were gathered at approximately 1
(baseline) 3, 5, and 13 months after miscarriage. Outcomes included
depression and grief, pure grief, and grief-related emotions. Content
for all three interventions was based on the Meaning of Miscarriage
Model, which consists of six emotionally challenging and meaning-laden
experiences that commonly accompany miscarriage. The process for all
interventions was based on Swanson's Caring Theory, which was derived
through three phenomological studies with individuals who had
personally or professionally dealt with loss and stress related to
childbearing.
The authors found that
- For women, NC resulted in accelerated resolution of depression,
compared with SC and CC.
- For men, compared with SC and CC, there was substantial evidence
that NC hastened resolution of depression.
- For women, compared with CC, both NC and SC provided weak
evidence of hastening PG resolution of grief-related emotions.
- For men, compared with SC, both CC and NC offered strong evidence
of accelerating resolution of pure grief and substantial to strong
evidence of hastening men's resolution of grief-related emotions.
- There was no evidence to suggest that SC, CC, or control was more
effective than NC in hastening men's or women's resolution of pure
grief, grief-related emotions, or depression.
The authors conclude that "whereas SC was quite effective in hastening
women’s grief resolution and CC positively accelerated men’s grief
resolution, it took three theory-based couples-focused nurse counseling
sessions to most adequately support couples’ emotional healing after
miscarriage."
Swanson KM, Hsien-Tzu C, Gramah JC, et al. 2009. Resolution of
depression and grief during the first year after miscarriage: A
randomized controlled clinical trial of couples-focused interventions.
Journal of Women’s Health 19(8):1-14. Abstract available at http://www.liebertonline.com/doi/abs/10.1089/jwh.2008.1202
Readers: More information is available from the following MCH Library
resources:
- Depression During and After Pregnancy: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_postpartum.html
Information is also available from the National Sudden and Unexpected
Infant/Child Death and Pregnancy Loss Resource Center at Georgetown
University as follows:
- Bereavement Support at
http://www.sidscenter.org/Bereavement/index.html
- Pregnancy Loss, Miscarriage, Stillbirth at
http://www.sidscenter.org/PregnancyLoss.html
- Miscarriage: A Selected Annotated Bibligraphy at
http://www.sidscenter.org/TopicalBib/Miscarriage.html
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MCH Alert © 1998-2009 by National Center for Education in Maternal
and
Child Health and Georgetown University. MCH Alert: Focus on Infant
Mortality is produced by
Maternal and Child Health Library at the National Center for Education
in Maternal and Child Health at Georgetown University under its
cooperative agreements
(U02MC00001 and U48MC08717) with the Maternal and Child Health Bureau,
Health
Resources and Services Administration, U.S. Department of Health and
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MANAGING EDITOR: Jolene Bertness
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COPYEDITOR/WRITER: Ruth Barzel
LIST ADMINISTRATOR: Beth DeFrancis Sun
MCH Alert
Maternal and Child Health Library
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