MCH Alert: Focus on Infant Mortality


Maternal and Child Health Library

MCH Alert: Focus on Infant Mortality is developed by the Maternal and Child Health Library in collaboration with the National Sudden Infant Death Resource Center. This and past issues are available online at http://www.mchlibrary.info/alert/archives.html and http://www.sidscenter.org/alert/archives.html.


  March 28, 2008

1. Documentary Series Examines Infant Mortality Within the Context of Racial and Socioeconomic Inequalities
2. Resource Incorporates Evolving Understanding of the Nature and Etiology of Disparities
3. Study Examines Whether Differences in Hospitals Where Infants are Born Contribute to Disparities
4. Review Summarizes Literature on Grief Subsequent to an Early Miscarriage
5. Article Assesses Relationship Between Maternal Caffeine Intake and Miscarriage Risk

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Special Notice: Training Course in Maternal and Child Health Epidemiology is a national program designed to build conceptual, technical, and analytic skills among professionals who have significant responsibility for collecting, processing, analyzing, and reporting maternal and child health data. The course will be held on June 2-7, 2008, in Chicago, Illinois, and is sponsored by the Health Resources and Services Administration's Maternal and Child Health Bureau (MCHB) and the Centers for Disease Control and Prevention as part of their ongoing effort to enhance the analytic capacity of state and local health agencies. The application form (due April 7, 2008) is available at http://www.positiveoutcomes.net/mchb_epi/MCHB_Epidemiology_Training_Course.doc.

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1. DOCUMENTARY SERIES EXAMINES INFANT MORTALITY WITHIN THE CONTEXT OF RACIAL AND SOCIOECONOMIC INEQUALITIES

Unnatural Causes: Is Inequality Making Us Sick? is a seven-part documentary series that explores ways in which social conditions affect population health and how some communities are extending lives by improving these conditions. Conceived as part of a larger impact campaign in association with leading public health, policy, and community-based organizations, the series is a production of California Newsreel with Vital Pictures. Episode 2 in the series, titled When the Bough Breaks, specifically examines the conditions that surround and negatively impact African-American women and their infants. Information about the documentary series and series objectives, episode descriptions, video clips, a discussion guide, and transcripts are available from the series' Web site. A searchable database containing articles, Web sites, data, interviews, interactivities, case studies, and educational and outreach materials is also provided. More information is available at http://www.unnaturalcauses.org.

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2. RESOURCE INCORPORATES EVOLVING UNDERSTANDING OF THE NATURE AND ETIOLOGY OF DISPARITIES

Racial and Ethnic Disparities in U.S. Health Care: A Chartbook offers a set of data and discussion intended to help policymakers, teachers, researchers, and practitioners begin to understand disparities in their communities and to formulate solutions. The chartbook, published by the Commonwealth Fund, is divided into seven chapters. Topics include changes in the U.S. population by race and ethnicity, income, and language; disparities in a number of the focus areas of the Healthy People 2010 initiative; the challenges minority Americans face in receiving needed health care (including both primary and specialized care); why insurance coverage varies by race and ethnicity; existing racial and ethnic disparities across the domains of quality articulated by the Institute of Medicine; and strategies that may lessen or eliminate disparities in health and health care. Data, including infant mortality data, are presented in charts throughout the document. Explanatory notes about the data in the charts are provided. The chartbook is available at http://www.commonwealthfund.org/usr_doc/Mead_racialethnicdisparities_chartbook_1111.pdf?section=4039.

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3.  STUDY EXAMINES WHETHER DIFFERENCES IN HOSPITALS WHERE INFANTS ARE BORN CONTRIBUTE TO DISPARITIES

"Black VLBW [very low birthweight] infants are more likely to be born in New York City hospitals with higher risk-adjusted neonatal mortality rates than are white VLBW infants," state the authors of an article published in the March 2008 issue of Pediatrics. This article presents findings from a study to investigate the association of hospital neonatal deaths (deaths within 28 days after delivery) and race. Specifically, the researchers sought to determine whether black VLBW infants are born in hospitals with the same mortality rates for VLBW infants as are white VLBW infants.

Data were obtained from New York City vital statistics birth and death files. Death files from January 1, 1996, through January 31, 2002, were linked to birth certificate data from January 1, 1996, through December 31, 2001. All live VLBW births (defined as birthweights of less than 1,500 g and greater than 499 g) that occurred in hospitals in the five boroughs of New York City were included (N=11,781). The researchers calculated risk-adjusted VLBW neonatal mortality rates (non-Hispanic black vs. non-Hispanic white) with and without hospital-level variables.

The authors found that
"The finding that, in New York City, black infants who are born too small systematically receive care in institutions with worse outcomes, compared with those where white infants receive care, demands immediate attention," state the authors. They conclude that "improving outcomes at the lowest-performing hospitals may produce the greatest benefit."

Howell EA, Hebert P, Chatterjee S, et al. 2008. Black/white differences in very low birth weight neonatal mortality rates among New York City hospitals. Pediatrics 121(3):e407-e415. Abstract available at http://pediatrics.aappublications.org/cgi/content/abstract/121/3/e407?rss=1.

Readers: More information is available from the following MCH Library resources:

- Knowledge Path: Infant Mortality at
http://www.mchlibrary.info/KnowledgePaths/kp_infmort.html

- Knowledge Path: Racial and Ethnic Disparities in Health at
http://www.mchlibrary.info/KnowledgePaths/kp_race.html

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4. REVIEW SUMMARIZES LITERATURE ON GRIEF SUBSEQUENT TO AN EARLY MISCARRIAGE

"The paucity of clear information as to the incidence, characteristics, and duration of grief following miscarriage suggests that practitioners can offer only suggestive guidelines as to what constitutes an adaptive or typical reaction to miscarriage," states the author of an article published in the March 2008 issue of the Journal of Women's Health. Although there is increasing acceptance that a miscarriage represents a significant loss experience, the empirical literature on grief following miscarriage remains limited. This article presents findings from a literature review on grief following miscarriage. The purpose of the review was to elucidate the nature of grief following an early miscarriage (before the 20th week of gestation); to determine the incidence, intensity, and duration of grief at this time; and to identify the variables that potentially moderate its intensity and duration.

The author conducted a search of Medline and Psych Info databases covering the period from January 1966 through January 2007 using the keywords miscarriage, spontaneous abortion, pregnancy loss in combination with grief, mourning, and bereavement. Further searches were then carried out using references cited in the identified papers. Studies were subsequently included in the review if the majority of women in a study sample experienced an early miscarriage, a standardized measure of perinatal grief was used, and assessment intervals were clearly specified.

The author found that
The authors conclude that "the similarity in the results of studies examining the duration and intensity of grief following miscarriage and the duration and intensity of grief following other types of losses supports using the general literature on grief to help guide patient expectations."

Brier N. 2008. Grief following miscarriage: A comprehensive review of the literature. Journal of Women's Health ahead of print. Abstract available at http://www.liebertonline.com/doi/abs/10.1089/jwh.2007.0505.

Readers: More information is available from the following MCH Library resource:

- Prenatal Care (bibliography) at
http://www.mchlibrary.info/action.lasso?-database=Biblio&-layout=Web&-response=/databases/BibLists/bib_prenatal.html&-MaxRecords=all&-DoScript=auto_search_prenatal&-search

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5. ARTICLE ASSESSES RELATIONSHIP BETWEEN MATERNAL CAFFEINE INTAKE AND MISCARRIAGE RISK

"The results from our prospective cohort study supported previous findings that high caffeine consumption during pregnancy may increase the risk of miscarriage," write the authors of an article published in the March 2008 issue of the American Journal of Obstetrics and Gynecology. Caffeine is among the most frequently ingested pharmacologically active substances in the world. Caffeine can readily cross the placental barrier to the fetus and has been reported to increase the risk of miscarriage. However, the effect of caffeine on the risk of miscarriage remains controversial because of methodological limitations in past studies. The objective of the present population-based prospective study was to examine the effect of maternal caffeine intake during pregnancy on the risk of miscarriage, taking into account a number of potential confounders, especially the impact of nausea and vomiting during pregnancy.

Study participants consisted of 1,185 women who resided in the San Francisco and South San Francisco areas and who were members of the Kaiser Permanente Medical Care Program (KPMCP). Participants had a positive pregnancy test during the 2-year period from October 1996 to October 1998. Information on exposure to caffeine was obtained during an in-person interview conducted soon after a woman's pregnancy was confirmed. Information on potential confounders, such as maternal age, race, education, household income, marital status, smoking, alcohol consumption, Jacuzzi use, exposure to magnetic fields (MF) during pregnancy, and symptoms related to pregnancy such as nausea and vomiting were also collected during the in-person interview.

The authors found that
The authors conclude that "it may be prudent to stop or reduce caffeine intake during pregnancy."

Weng X, Odouli R, Li D. 2008. Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study. American Journal of Obstetrics and Gynecology 198(3):279.e1-278.e8. Available at http://www.ajog.org/article/S0002-9378(07)02025-X/fulltext.

Readers: More information is available from the following MCH Library resources:

- Substance Use During Pregnancy (bibliography) at
http://www.mchlibrary.info/action.lasso?-database=Biblio&-layout=Web&-response=/databases/BibLists/bib_subusepreg.html&-MaxRecords=all&-DoScript=auto_search_subusepreg&-search

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MCH Alert © 1998-2008 by National Center for Education in Maternal and Child Health and Georgetown University. MCH Alert: Focus on Infant Mortality is produced by Maternal and Child Health Library at the National Center for Education in Maternal and Child Health under its cooperative agreements (U02MC00001 and U48MC08717) with the Maternal and Child Health Bureau, Health Resources and Services Administration, U.S. Department of Health and Human Services. The Maternal and Child Health Bureau reserves a royalty-free, nonexclusive, and irrevocable right to use the work for federal purposes and to authorize others to use the work for federal purposes.
 
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MANAGING EDITOR: Jolene Bertness
CO-EDITOR: Tracy Lopez
COPYEDITOR/WRITER: Ruth Barzel
LIST ADMINISTRATOR: Beth DeFrancis Sun

MCH Alert
Maternal and Child Health Library
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